The History of Noggin - The Hair Restoration Inter Cell Messenger

  • david bryant

Noggin, as we all know is a euphemism for the head.  It is one of those quaint English words that has become part of the normal vernacular, that would have no meaning outside the UK and would make people stop and stare if they had not heard of it before.  ‘I just banged my noggin’, or ‘my daughter hurt her noggin at school’ , seems normal to us Brits, yet completely alien to other cultures. 

Yet Noggin is also the name of a Growth Factor that is one the main ingredients for a new exciting range of Hair Restoration products.  Noggin (the Growth Factor) has not be named as part of a clever marketing or advertising review but is actually the name of a powerful and cutting edge Growth Factor in the new SkinGenuity Hair Restoration range. 





 Noggin is in fact a complex protein that was discovered in the 90’s and was named due to the fact that it produced embryos with large heads[i].  It is ironic that one of the main uses of Noggin is to stimulate the stem cells that remain dormant when hair is lost[ii].  Noggin is a well-researched protein that has many uses but in combination with other focussed and targeted Growth Factors has proven to be effective at improving the coverage and thickness of hair on patients who are suffering from hair loss

 The SkinGenuity Hair Restoration range uses Growth Factors as part of the treatment regimen. Due to some significant scientific advances, Growth Factors can now be used in aesthetic treatments, including hair restoration.  The SkinGenuity Growth Factors all have their part to play in the ensuring the patient has the best chance of improving their hair density and coverage. 

  • SkinGenuity Hair Restoration uses Growth Factors that are nano-encapsualted, so they penetrate the hair follicles
  • Noggin is joined in the SkinGenuity Hair Restoration range by 9 other Growth Factors that have been proven individually to help, inducing the anagen phase in resting hair follicles[iii], stimulate the cells that cause normal hair follicle growth[iv] and stimulate overall hair growth[v].
  • The SkinGenuity Hair Restoration treatment is a protocol that uses in clinic treatment followed by home use.
  • There is no requirement to take blood from the patient to apply the Growth Factors within clinic treatments such as micro needling.

 SkinGenuity Hair Restoration is most effective when used as part of a treatment protocol with the patient buy in.

In Clinic Treatment



If you have your own micro needling system in house then the in clinic treatment would be micro needling in combination with the SkinGenuity Hair Restoration serum.  This is applied to the scalp before and after needling


If you do not use Micro needling then you can use the Empress needling system in combination with the Empress Regenerative solution with our 1.0mm needles  


Once the patient has had in clinic treatment they can then purchase the home care kit, which is a two-step process that will ensure that patient has the best chance of improving their hair loss


Firstly, the patient can carry on with the needling on their scalp, by using the Empress needles in combination with the Noggin and his friends in the SkinGenuity Hair Restoration serum. This should be done every other day


The SkinGenuity home kit also contains an innovative brush which delivers a clinically proven combination of botanical and essential oils that will enhance the effect of the needling.  This is done twice daily




The key to the success of this treatment protocol is patient compliance and we have ensured that the cutting edge technology has a cutting edge packaging and presentation.  The SkinGenuity Hair Restoration home kit is presented in a video box that give clear instructions on how to use the system and can be personalised to the individual clinic. 


It is clear that some scientists have a sense of humour and naming Noggin – Noggin is an example.  Hopefully the use of Noggin as part of a combination of Growth Factors and the home treatment will ensure that the patients who suffer from hair loss will now have something that can be used which is an alternative to expensive and in-practical treatments such as PRP and an adjunct to the current therapies available.


[i] Oppenheimer SB (1995). "The Discovery of Noggin". The American Biology Teacher. 57 (5): 264.

[ii] Botchkarev VA1Botchkareva NV; Noggin is required for induction of the hair follicle growth phase in postnatal skin.FASEB J. 2001 Oct;15(12):2205-14.

[iii] Lin WH1, Xiang LJ ; Fibroblast growth factors stimulate hair growth through β-catenin and expression in C57BL/6 mice; Biomed Res Int. 2015;2015;Epub 2015 Jan 1.

[iv] D. M. DanilenkoB. D. Ring; Keratinocyte growth factor is an important endogenous mediator of hair follicle growth, development, and differentiation. Normalization of the nu/nu follicular differentiation defect and amelioration of chemotherapy-induced alopecia; Am J Pathol. 1995 Jul; 147(1): 145–154. 

[v] Therapeutic role of human hepatocyte growth factor (HGF) in treating hair loss. PeerJ. 2016 Nov 1;4:e2624. doi: 10.7717/peerj.2624. eCollection 2016;